Molecular and Genetic Medicine

Department of Science, University of Toronto, Canada

Publications

• Mini Review   
  A Review on 3D Organoid Models Over Stem Cell Based Cardiovascular Regrowth
  Author(s): Lauren Brunelli*
  
  Over the past few decades, stem cell-based cardiac regeneration has emerged as a promising therapy for patients with heart failure, a condition that affects millions of people worldwide. Stem cells have the ability to differentiate into various types of cells, including heart cells, and can potentially be used to replace damaged or dead heart tissue. One of the challenges in using stem cells for cardiac regeneration is creating a suitable environment for their growth and differentiation. Traditional two-dimensional (2D) culture methods have limitations in mimicking the complex three-dimensional (3D) environment of the heart. This is where 3D organoid models come into play. Organoids are 3D structures that can be grown from stem cells, which can self-organize and differentiate into specific cell types, mimicking the structure and function of organs. In the context of cardiac regenerati.. Read More»
  DOI: 10.37421/1747-0862.2023.17.598

  Abstract HTML PDF