Journal of Pediatric Neurology and Medicine

Department of Biotechnology, Shree Ramswaroop Memorial University, Uttar Pradesh, India

Publications

• Commentary   
  Sickle Cell Disease in Children
  Author(s): Jyoti Rawat*
  
  The capacity to recognize babies with sickle cell weakness who are probably going to have extreme entanglements further down the road would allow precise visualization and fitting of treatment to coordinate illness related dangers and encourage arranging of clinical preliminaries sickle cell anaemia (SCA; homozygous sickle haemoglobin [HbS], i.e. HbSS) occurs when thymine is substituted for adenine in the 6th codon of the beta globin gene, resulting in the production of valine (a hydrophobic amino acid) instead of glutamic acid, which is hydrophilic. Although all SCA patients share the same genetic mutation, the clinicalcourse is highly variable between patients. The highest sickle cell trait (HbAS) carrier rate is present in families who trace their ancestry to malaria endemic regions. In addition to homozygous SCA, other sickle-related haemoglobinopathies occur when HbS is inherited.. Read More»
  DOI: 10.35248/2472-100X.20.5.147

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