Journal of Nephrology & Therapeutics

Department of Nephrology, Sultan Qaboos University Hospital, Muscat, Oman

Publications

• Expert Review   
  Regional Expert Opinion on Tolvaptan Therapy for ADPKD: Bridging Gaps in the GCC and MENA Regions
  Author(s): Mustafa Jamal Ahmed*, Omer Ali, Mohamed H. Hassan, Ali AlSahow, Anas Al-Yousef, Nuria S. Perez Romano, Dawood Al Riyami, Hormaz Dastoor, Wafa A. Altuwaijri, Muhammad Ubaid Ullah and Mohammed Alshehri
  
  Autosomal Dominant Polycystic Kidney Disease (ADPKD) constitutes one of the most common hereditary renal disorders, characterized by progressive cystic enlargement and a subsequent decline in renal function. Although the condition presents a significant health burden in regions with high rates of consanguinity, such as the Gulf Cooperation Council (GCC) and the Middle East and North Africa (MENA), comprehensive regional data on its prevalence, diagnosis and management remain limited. Tolvaptan, a selective antagonist of the vasopressin V2 receptor, is presently the sole disease-modifying therapy approved for decelerating the progression of ADPKD. This review is based on the synthesis of current literature amalgamated with the opinions of nephrologists (from the Kingdom of Saudi Arabia, Kuwait, Oman, Bahrain and the United Arab Emirates) convened to develop guidance on the utilization .. Read More»
  

  Abstract PDF