Journal of Clinical Anesthesiology: Open Access

Center for Clinical Research and Innovation, Kobe City Medical Center General Hospital, Japan

Publications

• Research   
  Intraoperative Administration of Dexmedetomidine Improved Moderately Postoperative Analgesia of Laparoscopic Colorectal Surgery: A Prospective, Randomized, Controlled Trial
  Author(s): Hiroshi Yamashita*, Yudai Hasushita, Chisato Miyakoshi and Hiroyuki Mima
  
  Purpose: Although laparoscopic surgery is generally considered minimally invasive, some patients have difficulty in postoperative analgesia. This study investigated the possibility of improving postoperative analgesia by intraoperative dexmedetomidine infusion. Methods: This study was a two-arm, single-blind, randomized, intergroup trial. A total of 64 patients having undergone laparoscopic colorectal surgery were included, which were randomly divided into two: dexmedetomidine administration (DEX group) vs. no-administration (control group), with the former received DEX at 0.5 μg/kg/h. The primary endpoint was the maximum Numerical Rating Scale (NRS) pain score at rest within 4 hours after returning to the High Care Unit (HCU). The secondary endpoints included the NRS pain score at rest on the following morning, the doses of analgesics an.. Read More»
  DOI: 10.37421/jcao.2022.6.127

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