Department of Mechanical and Industrial Engineering, Atlantic Technology University, MET Gateway, Galway, Ireland
 Research   
								
																Fabrication, Characterization and Optimization of Multiphasic Zein/Cartilage-derived Matrix/CP/Gelatin Composite Scaffolds for Potential Bone Tissue Engineering Applications 
																Author(s): Azadeh Shahroodi, Sogol Hooshyar, Davood Yari, Jebraeil Movaffagh and Ali Moradi*             
								
																
						 Introduction: Creating an ideal scaffold for bone tissue engineering requires specific characteristics. Composite materials, combining the
  advantages of polymers and ceramics, offer tailored properties and enhanced functionality. This study aimed to fabricate, characterize and optimize
  multi-phasic composite scaffolds with spiral backbones for potential bone tissue engineering applications.
Methods: Composite scaffolds were fabricated via electrospinning using 24.5% Zein and varying concentrations of Calcium Phosphate (CP) (15%,
  20% and 25%). Ribbon-shaped electrospun Zein/CP composite mats were structured into spiral forms, placed in cylindrical Teflon molds, filled
  with a blended slurry (Zein/cartilage-derived matrix/CP/gelatin), snap-frozen and lyophilized to form multi-phasic composite scaffolds. Mechanical,
  FESEM and FTIR a.. Read More»
						  
																DOI:
								10.37421/2157-7552.2024.15.351															  
Journal of Tissue Science and Engineering received 807 citations as per Google Scholar report