Department of Psychiatry and Neurochemistry, University of Gothenburg, Gothenburg, Sweden
Mini Review
Serum-based Stability of Circulating MicroRNAs
Author(s): Andreas Göteson*
Our goal was to find novel protein associations that could serve as biomarkers for bipolar disorder that could be used in the real world. In order
to accomplish this, we analyzed 201 distinct proteins found in blood serum from two distinct cohorts of patients with bipolar disorder and healthy
controls using the proximity extension assay. After controlling for relevant covariates, we discovered 32 proteins that significantly correlated with
bipolar disorder in both case-control cohorts. Despite the fact that ten proteins have previously been linked to bipolar disorder, twenty-two of
these findings are novel to the disorder. Matrilysin, pro-adrenomedullin, chitinase-3-like protein 1, C-C motif chemokine 3, interleukin 10, growth/
differentiation factor 15. After that, we estimated the variance in serum protein concentrations that could have been explained by psychiat.. Read More»
DOI:
10.37421/2155-9929.2022.13.555
Molecular Biomarkers & Diagnosis received 2054 citations as per Google Scholar report
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