Molecular and Genetic Medicine

Yasuyuki Miyakura

Publications

• Mini Review
  Significance of the Difference in the Size of Liver Tumors in the Management of Patients with Colorectal Liver Metastases
  Author(s): Kosuke Ichida, Koichi Suzuki, Taro Fukui, Yuji Takayama, Nao Kakizaw, Yuta Muto, Takaharu Kato, Fumi Hasegawa, Fumiaki Watanabe, Yuji Kaneda, Rina Kikugaw, Masaaki Saito, Shingo Tsujinaka, Kazushige Futsuhara, Yasuyuki Miyakura, Hiroshi Nod, Hirokazu Kiyozaki and Toshiki RikiyamaKosuke Ichida, Koichi Suzuki, Taro Fukui, Yuji Takayama, Nao Kakizaw, Yuta Muto, Takaharu Kato, Fumi Hasegawa, Fumiaki Watanabe, Yuji Kaneda, Rina Kikugaw, Masaaki Saito, Shingo Tsujinaka, Kazushige Futsuhara, Yasuyuki Miyakura, Hiroshi Nod, Hirokazu Kiyozaki and Toshiki Rikiyama
  
  Background: The combination of chemotherapy and surgery is currently accepted for the treatment of patients with technically resectable colorectal liver metastases. It is, however, hard to determine which of these modalities should be the forward treatment. In this study, we assessed the usefulness of the difference in tumor size assessed in pretherapeutic imaging in the selection of chemotherapy in these patients. Methods: We present a retrospective review of 80 consecutive colorectal liver metastases without extrahepatic tumors. The relapse-free survival (RFS), progression-free survival (PFS) and overall survival (OS) were evaluated and compared between patients who underwent surgery (n=66) and chemotherapy (n=14) according to clinical features. In particular, we addressed pretherapeutic imaging studies including the distribution and numbe.. Read More»
  

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