Journal of Tissue Science and Engineering

Vuk Savkovic

Publications

• Research Article
  Melanocytes from the Outer Root Sheath of Hair Follicles Cultivated on Collagen Membrane Improve their Melanotic Properties
  Author(s): Vuk Savkovic, Katharina Sülflow, Katrin Rabe, Marie Schneider and Jan-Christoph SimonVuk Savkovic, Katharina Sülflow, Katrin Rabe, Marie Schneider and Jan-Christoph Simon
  
  Local depigmentation disorders such as Vitiligo are detrimental for both physiological and psychological reasons and demand a causal, non-invasive treatment. The only available treatment of a kind at present is melanocyte transplantation, disadvantageously dependent on an invasive skin biopsy as melanocyte source. We have previously reported our work on an autologous, non-invasive method of differentiating melanocytes from the outer root sheath of human hair follicles for use in transplantation treatment. Choice of a suitable biocompatible, biodegradable carrier as a temporary niche for transplanted melanocytes can be crucial in such applications. Therefore, we tested decellularized bovine collagen type I scaffold membranes as a candidate for a favourable carrier of the hair follicle melanocytes. This study provides an additional insight to the reported upgraded explant m.. Read More»
  DOI: 10.4172/2157-7552.S11-004

  Abstract PDF