Pulmonary & Respiratory Medicine

Umar Osman

Publications

• Case Report
  Bronchial Necrosis Following Bevacizumab and Stereotactic Body Radiotherapy for Treatment of Metastatic Breast Cancer
  Author(s): Umar Osman and Christopher R GilbertUmar Osman and Christopher R Gilbert
  
  Bevacizumab is an emerging therapy with widespread use in the treatment of advanced malignancies. We describe a young female with metastatic breast cancer that underwent stereotactic body radiation during treatment with bevacizumab after the discovery of a new metastatic focus within the lung parenchyma. Approximately one year later she presented with a progressive foul smelling cough and dyspnea. Bronchoscopy revealed extensive necrotic destruction of the bronchus intermedius. Airway necrosis may be a rare adverse event associated with the use of bevacizumab, especially with concomitant radiotherapy. .. Read More»
  DOI: 10.4172/2161-105X.1000345

  Abstract PDF