Israel						                            
                            
						
 Review Article
												Biomarkers for the Detection of Pre-Cancerous Stage of Cervical Dysplasia 						
Author(s): Paz  Elia, Stella  Raizelman, Esti  Katorza, Yosef  Matana, Offer  Zeiri, Zvi  Boger, Manuela  Cervelli, Paolo  Mariotini, Cristina  Vallone, Fabrizio  Signore and Yehuda  ZeiriPaz  Elia, Stella  Raizelman, Esti  Katorza, Yosef  Matana, Offer  Zeiri, Zvi  Boger, Manuela  Cervelli, Paolo  Mariotini, Cristina  Vallone, Fabrizio  Signore and Yehuda  Zeiri             
						
												
				 Introduction: Early diagnosis of cancer can dramatically increase healing probability. However many cancer detection methods are time-consuming, invasive, and require skilled medical staff and/or expensive detection systems. Cervical cancer is the fourth most common malignant disease among women, and the fourth leading cause of cancer death in women worldwide.
Aim: This pilot study sought to identify reliable biomarkers indicative of early stages of cervical dysplasia, by analysis of changes in volatile organic compound composition in urine samples.
Methods: Urine samples of 17 patients with cervical intraepithelial neoplasia (CIN I) and of 9 healthy female subjects were used. The sample composition was analyzed using Gas-Chromatography-Mass-Spectrometry. The statistical analysis of the data was performed using sup.. Read More»
				  
												DOI:
												 10.4172/2155-9929.1000255 
																	  
Journal of Molecular Biomarkers & Diagnosis received 2054 citations as per Google Scholar report