Medicinal Chemistry

Sobia Ahsan Halim

Biography

 She holds a Ph.D from Dr. Panjwani Center Molecular Medicine & Drug Research Center, International Center for Chemical & Biological Sciences, University of Karachi in 2012. She Served as Lecturer in Department of Biochemistry, Jinnah University for Women, Karachi (June 2011-February 2012). Taught courses to B.S: Introductory Biochemistry -I, Introduction to Neurochemistry, Nutrition and Dietetics, Metabolism-I and Nutrition and Biochemical Techniques-II. Taught Courses to M.S: Communication of Sciences, Research Methodology. Her research interest covers Fragment based library designing for entire druggable genome using virtual chemogenomics approach. Benchmarking and validation of widely used docking and scoring tools for several medicinally. Molecular modeling of small organic molecules and several potential drug targets by molecular docking. Design of new immune-modulators and bio-active molecules for a range of pharmaceutically important targets using computer aided modeling techniques. Ligand based and structure based pharmacophore design. Generation and screening of large virtual combinatorial compound libraries. Determination of molecular activity using 3D-QSAR calculations. Molecular Dynamics simulations studies of protein-ligand complex.

Research Interest

 Fragment based library designing for entire druggable genome using virtual chemogenomics approach. Benchmarking and validation of widely used docking and scoring tools for several medicinally. Molecular modeling of small organic molecules and several potential drug targets by molecular docking. Design of new immune-modulators and bio-active molecules for a range of pharmaceutically important targets using computer aided modeling techniques. Ligand based and structure based pharmacophore design. Generation and screening of large virtual combinatorial compound libraries. Determination of molecular activity using 3D-QSAR calculations. Molecular Dynamics simulations studies of protein-ligand complex.