Veterinary Science & Technology

Singh R

Publications

• Review Article
  Application of Microarray in Animal Disease Pathogenesis and Diagnosis
  Author(s): Beena V, Pawaiya RVS, Gururaj K, Shivasharanappa S, Karikalan M and Singh RBeena V, Pawaiya RVS, Gururaj K, Shivasharanappa S, Karikalan M and Singh R
  
  Microarray is a plethora of multiple genetic data. It is a collection of microscopic spots contains picomoles (10-12 moles) of a specific sequences (DNA, cDNA, cRNA, Oligonucleotides), known as probes. These probes hybridize with specific nucleic acid sequence called targets which are labelled with a fluorescent dye. Hybridization property between nucleotides were utilized in this and the signals produced are scanned and image data is converted to raw data using various softwares. Microarray has number of applications in the area of evolution biology, pathway analysis, toxicogenomics, pharmacogenomics, forensics, oncology and disease diagnostics and characterization. The genes responsible for several stages of cell to cell interaction of pathogens from adhesion to entry into the host cell and evading the host immune mechanism can be studied. Comparative genomic hybridization,.. Read More»
  DOI: 10.4172/2157-7579.1000402

  Abstract PDF