Molecular and Genetic Medicine

Rajshekhar Jaka

Publications

• Research Article
  Secondary Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy (CRS+HIPEC) for Recurrent Epithelial Ovarian Cancer (EOC): Indian Experience
  Author(s): Somashekhar SP, Prasanna G, Rajshekhar Jaka, Amit Rauthan, Murthy HS and Sunil KaranthSomashekhar SP, Prasanna G, Rajshekhar Jaka, Amit Rauthan, Murthy HS and Sunil Karanth
  
  Background: Cytoreductive surgery combined with hyperthermic intraperitoneal chemotherapy (CRS+HIPEC) has been proposed as treatment for recurrent epithelial ovarian carcinoma. We evaluated the outcomes of CRS +HIPEC in recurrent epithelial ovarian cancers, in Indian patients. Method: In this prospective non-randomized study between February 2013 and January 2015, 26 patients with advanced recurrent EOC, with no extra-abdominal disease treated with secondary CRS+HIPEC in a tertiary care cancer institution, Southern India, were analyzed. Belmonte® hyperthermia (HIPEC) pump with cisplatin 100 mg/m2, 41.5°C to 43°C for 90 minutes, in platinum sensitive cases and doxorubicin 15 mgs/m2 + cisplatin 75 mg/m2 in platinum resistant cases was used. Result: Among twenty six patients 18 were upfront and 8 were post.. Read More»
  DOI: 10.4172/1747-0862.1000220

  Abstract PDF