Cardiovascular Diseases & Diagnosis

Minoo N Kavarana

Publications

• Research Article
  Pediatric Mechanical Support with an External Cardiac Compression Device
  Author(s): Minoo N Kavarana, Howard M Loree II, Robert B Stewart, Michael T Milbocker, Robert L Hannan, George M Pantalos and Robert TV KungMinoo N Kavarana, Howard M Loree II, Robert B Stewart, Michael T Milbocker, Robert L Hannan, George M Pantalos and Robert TV Kung
  
  The PediBooster external cardiac compression device is a minimally invasive, non-blood contacting Biventricular Assist Device (BiVAD) intended for pediatric use. It is being developed as a palliative therapy for acute Postcardiotomy Shock (PCS). The PediBooster extracardiac wrap is pneumatically actuated to circumferentially compress the heart, providing co-pulsation support. Attachment is via a novel hydrogel coating. Early versions of the wrap were tested in vivo using a single ventricle congenital heart disease model with postcardiotomy shock, which proved unstable and demonstrated high peri-operative mortality. The final wrap design was tested in 4 acute studies with piglets (5.1 ± 0.3 kg), where the combination of ASD and PA banding induced acute right ventricular dysfunction. Data collected included routine hemodynamic values, TEE, video of the exposed heart, and cardiac .. Read More»
  DOI: 10.4172/2329-9517.1000105

  Abstract PDF