Journal of Clinical Case Reports

ISSN: 2165-7920

Open Access

Miguel Hernandez Pampaloni

505 Parnassus Avenue, M-396 San Francisco, CA, 94143
United States

  • Case Report
    Voriconazole-Associated Periostitis in a Heart Transplant Patient
    Author(s): Miguel Hernandez PampaloniMiguel Hernandez Pampaloni

    A 60 year-old female with a history of a heart transplant was treated with voriconazole for presumed pulmonary aspergillosis. After approximately three months, she began to experience progressively worsening musculoskeletal pain. Her presentation was notable for widespread tenderness, a lack of digital clubbing, and elevated alkaline phosphatase. Bone scintigraphy demonstrated increased activity at multiple locations correlating with the patient’s pain. Periostitis was identified in these locations on radiographs. A few months after discontinuing voriconazole, the patient’s pain had resolved, alkaline phosphatase had normalized, and abnormal activity on scintigraphy had markedly improved. .. Read More»
    DOI: 10.4172/2165-7920.1000166

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