Journal of Hypertension: Open Access

Louise Brinth

Publications

• Research Article
  Baroreflex Sensitivity in Relation to Clinical Characteristics in Subject Aged 40 to 80 Years
  Author(s): Louise Brinth, Kirsten Pors, Tabassam Latif, Andreas Kjær and Jesper MehlsenLouise Brinth, Kirsten Pors, Tabassam Latif, Andreas Kjær and Jesper Mehlsen
  
  Baroreflex function measured as baroreflex sensitivity (BRS) mirrors an integrated capacity of the autonomic nervous system. We aimed to assess the relationship between measures of BRS and age and relevant clinical characteristics. 80 subjects participating in the Copenhagen City Heart study (43 women) with a mean age of 59 ± 11 years (range 41-79 years) were included. Baroreceptor activity was quantified through the Valsalva manoeuvre (VM) and as a spontaneous function. BRS was tested against age, gender, smoking status, body size and predicted risk of coronary heart disease based on the Framingham score. BRS was found to decline with age, but this change disappeared when correcting for the age related increase in systolic blood pressure. We found that the VM-derived indices of sympathetic vascular control declined with age as did the vagally controlled hea.. Read More»
  DOI: 10.4172/2167-1095.1000152

  Abstract PDF