Journal of Hypertension: Open Access

Lene Kjær Olsen

Publications

• Research Article
  Evaluation of Renal Denervation by 24-Hour Ambulatory Blood Pressure and Quantified Antihypertensive Medication
  Author(s): Lene Kjær Olsen, Anne-Lise Kamper DMSc, Jesper Hastrup Svendsen, Lia EviBang, Marie Frimodt-Møller, HenningKelbæk and Bo Feldt- RasmussenLene Kjær Olsen, Anne-Lise Kamper DMSc, Jesper Hastrup Svendsen, Lia EviBang, Marie Frimodt-Møller, HenningKelbæk and Bo Feldt- Rasmussen
  
  Background: Previous studies of renal denervation (RDN) have mainly focused on the effect on office blood pressure (BP) and number of antihypertensive drugs although these are known as sub-optimal endpoints. Aim: The aim of this study was to evaluate the effect of RDN by combining 24-hour ambulatory blood pressure (ABP) measurements and quantified antihypertensive medication at 12 months after RDN. Methods: Fifty-one patients (71% men, mean age 56 years) with resistant hypertension were treated with RDN. Office BP and ABP were measured at baseline and 6 and 12 months after RDN. Concomitantly the administration of antihypertensive drugs was assessed by their total defined daily dose (DDD). Results are presented as mean values ( ± SD)). Results: The change in daytime systolic ABP at 6 and 12 months was -8.6 (22.5) (P=0.01) and -4.2 (22.3) mmHg (P=NS). Quantified antihypertensive me.. Read More»
  DOI: 10.4172/2167-1095.1000200

  Abstract PDF