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Journal of Clinical & Medical Genomics

ISSN: 2472-128X

Open Access

Laila Y AL-Ayadhi


Saudi Arabia

Publications
  • Research Article
    Genetic Markers Association in Autism Spectrum Disorder
    Author(s): Nadra E Elamin and Laila Y AL-AyadhiNadra E Elamin and Laila Y AL-Ayadhi

    Although the etiology of autism spectrum disorder (ASD) is still unclear, multiple factors have been suggested to be involved in its pathogenesis. There is a strong evidence for multiple interacting genetic factors as the main cause of autism. Hundreds of genes and genetic mutations that are involved in autism development were identified, and thus serve as useful genetic markers for identification of autism. Those genes play a key role in brain development, or may code for immune proteins. Numerous studies have suggested that autism can be inherited based on earlier twins studies which showed that monozygotic (MZ) twins had higher concordance rates than dizygotic (DZ) twins for ASDs. In this review we consider the genetic factors that underlie the pathogenesis of autism and their contribution to the disease outcome. In conclusion, candidate genes studies will highlight the role of int.. Read More»
    DOI: 10.4172/2472-128X.1000132

    Abstract PDF

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