Department of Neurosurgery, Kitasato University School of Medicine, Kanagawa, Japan.
Determination of active and total HMG-CoA reductase inhibitors concentrations, Pharmacokinetic analysis, Blood sampling, Total HMG-CoA reductase inhibitors, Active HMG-CoA reductase inhibitors, Plasma concentrations of HMG-CoA reductase inhibitor were determined up to 8 h thereafter. Grapefruit juice increased the area under the plasma concentration-time curves.
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