Medicinal Chemistry

Kunapareddy CS

Biography

Kunapareddy CS is a faculty member of Department of Natural Sciences, Western New Mexico University, Silver City, USA.His research article was on Clotrimazole as a Cancer Drug Clotrimazole and its derivatives have been shown to decrease rates of cancer cell proliferation, induce G1 phase arrest, and promote pro-apoptotic factors, which lead to cell death.

Research Interest

Clotrimazole; Calmodulin; Human melanoma; Hexokinase, Mechanism of Action Against Cancer, Hexokinase is the enzyme that phosphorylates glucose in the first and the rate-limiting steps of glycolysis. HK has four isoforms HK1, HK2, HK3, and HK4.Mechanism of action is based on the inhibition of mitochondrial bound glycolytic enzymes and calmodulin.

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