Journal of Hypertension: Open Access

Jane ES Thompson

Publications

• Research Article
  Matrix Metalloproteinase-9 and Augmentation Index are Reduced with an 8-Week Green-Exercise Walking Programme
  Author(s): Jane ES Thompson, Richard Webb, Paul Hewlett, David Llewellyn and Barry J McDonnellJane ES Thompson, Richard Webb, Paul Hewlett, David Llewellyn and Barry J McDonnell
  
  Objectives: MMP-9 is involved in degrading the Extracellular Matrix (ECM); specifically elastin, which provides elasticity to the arterial wall. Elastin degradation and restructuring of the ECM results in increased vascular remodelling and arterial stiffness. Conversely, exercise improves age-related vascular stiffening. Therefore, this study aimed to investigate whether participation in a green-exercise programme affects vascular haemodynamics and mRNA expression of MMP-9. Methods: Thirty-six healthy, sedentary individuals (44 ± 2yrs; not taking any cardiovascular-acting medication) joining a moderate-intensity, aerobic green-exercise programme, were recruited. At baseline and 8-weeks into the programme, physical activity (measured in weekly MET-minutes [IPAQ]), supine Mean Arterial Blood Pressure (MAP), Augmentation Index (AIx) and aort.. Read More»
  DOI: 10.4172/2167-1095.1000127

  Abstract PDF