Journal of Bioanalysis & Biomedicine

Dr. Istvan Boldogh is working at Division of Pulmonary Critical Care & Sleep Medicine, University of Texas Medical Branch, USA. Dr. Boldogh’s program is centered on studies of oxidative stress, which, due to reactive oxygen species (ROS), is continuously generated during respiration, and is also induced by exogenous environmental pollutants. ROS is also generated endogenously by intracellular oxidases due to inflammation, infections and drug treatment. Although a variety of cellular processes have evolved to eliminate ROS, oxidative stress occurs when there is an imbalance between production of ROS and antioxidant defense.