Journal of Molecular Biomarkers & Diagnosis

Gerardo Salerno

Publications

• Research Article
  The Utility of Pyrogenic Cytokine (IL-1β, TNF-α and IL-6) Detection In Risk Stratification of Critically lll Febrile Patients in Emergency Department
  Author(s): Francesco Travaglino, Gerardo Salerno, Veronica Russo, Mariateresa Corsetti, Rosaria D’Urso, Patrizia Cardelli, Maria Rosaria Torrisi, Vincenzo Visco and Salvatore Di SommaFrancesco Travaglino, Gerardo Salerno, Veronica Russo, Mariateresa Corsetti, Rosaria D’Urso, Patrizia Cardelli, Maria Rosaria Torrisi, Vincenzo Visco and Salvatore Di Somma
  
  Objective: Aim of our study was to evaluate the prognostic value of pyrogenic cytokines (IL-1β, TNF-α and IL-6) detection associated with Mid regional pro-Amedullin (MR-proADM) and the APACHE II score in febrile patients admitted to the Emergency Department (ED). Material: 64 patients in the Emergency Room (ER) during a period of 12 months with body temperature >37°C were recruited for this study. In order to compare MR-proADM and cytokine values, a control group of 40 healthy volunteers was enrolled. For each subject, the APACHE II score was calculated. Result: MR-proADM and cytokines were significantly higher in patients compared to controls (p<0.0001). When APACHE II score was correlated to MR-proADM and cytokines and grouped into quartile, it showed a significant increase in TNF-α and.. Read More»
  DOI: 10.4172/2155-9929.1000188

  Abstract PDF