Spain						                            
                            
						
 Case Report
												Acute Submandibular Oncogenes in Myelodysplastic Syndrome: A Rare Report 						
Author(s): MarÃÂa Luisa  Navarrete, Fernando  Morell, Juan Fernando  Fuentes, Nuria  Ortiz, Pilar  Coscojuela and Angel  GarcíaMarÃa Luisa  Navarrete, Fernando  Morell, Juan Fernando  Fuentes, Nuria  Ortiz, Pilar  Coscojuela and Angel  García             
						
												
				 Myelodysplastic syndromes (MDS) are hematological diseases with a wide clinical spectrum of manifestations. We present a 66 year old patient who was referred to our department with an acute submandibular growth that was first noticed 2 weeks ago. It hasn’t responded to standard treatment. Multiple studies were performed, and they revealed in filtrate of mielodisplastic cells, refractory anemia with excess blasts in transformation (RAEB-T) subtype according to the FAB classification. Combined chemotherapy couldn’t stop the disease’s progression and the patient died from a pulmonary infection 3 months after the onset of symptoms. Leukemic infiltration of the submandibular gland in mielodisplastic syndrome hasn’t been previously described in literature, so this seems to be the first reported case of extra medullary hematopoiesis resulting in an ac.. Read More»
				  
												DOI:
												 10.4172/2157-7552.1000115 
																	  
Journal of Tissue Science and Engineering received 807 citations as per Google Scholar report