Molecular Biomarkers & Diagnosis

ISSN: 2155-9929

Open Access

Feng Chen

School of Stomatology, ,
#22 Zhongguancun South Road, Haidian District, Beijing 100081

  • Review Article
    Salivary Peptidomic Analysis -The Extension of Proteomics
    Author(s): Jieni Zhang, Xueji Zhang, Qingwei Ma, Jiuxiang Lin and Feng ChenJieni Zhang, Xueji Zhang, Qingwei Ma, Jiuxiang Lin and Feng Chen

    Nowadays, proteomic-related studies have developed rapidly and improvement has been made in the scientific and technological fields. Besides the proteome, the peptidome with low molecular weight has apparently attracted increasing attention in recent years too. The peptidome performs a large array of vital biological functions to contribute to homeostasis in the certain tissues. However, due to the interference by high-abundance proteins in complex biological body fluids such as saliva and serum, selective enrichment of peptides with low molecular weight is the first and most important step before analyzing the peptidome. This review mainly illustrates the general concept of the peptidome, specific methods of saliva collection, advanced peptidomic technologies and the recently developed peptidomic-related reports, as well as some limitations of the application in salivary peptidome. T.. Read More»
    DOI: 10.4172/2155-9929.1000142

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