Cartilage Regeneration Using a Fibrin and Autologous Cultured Chondrocytes Mixture in a Canine Model
Author(s): Chang-Kwon Ko, Eun-Young Lee, Jae-Deog Jang, Seok-Jung Kim, Dong-Sam Suh and Cheong-Ho ChangChang-Kwon Ko, Eun-Young Lee, Jae-Deog Jang, Seok-Jung Kim, Dong-Sam Suh and Cheong-Ho Chang
Background: Various surgical methods have been designed to avoid the necessity of using periosteum, i.e. an operative weak point of autologous chondrocyte implantation (ACI) which is a representative method for treating articular cartilage injury. This study was performed in the attempt to develop a simple, injectable type of ACI to in order facilitate the surgical process. Methods: Seven of 10 dogs were used for the injectable type ACI using fibrin, while the remaining three dogs were used for implantation according to the previous surgical method using periosteum. The left knee of each dog was incised in order to expose the medial femoral condyle, and a circular defect was then made to 5mm in diameter on the articular cartilage of the exposed medial femoral condyle so that chondrocyte.. Read More»
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Jan 01, 1970
Accepted Date: Jan 01, 1970
Published Date: Jan 01, 1970