Evaluation of the Open-Access Video Tracking Programme Swarm Sight to Evaluate Lethargy in a Ferret Model of Influenza Infection
Author(s): Aeron C. Hurt, Celeste Ming-Kay Tai and Ding Yuan OhAeron C. Hurt, Celeste Ming-Kay Tai and Ding Yuan Oh
As an animal model of influenza, ferrets are uniquely capable of displaying clinical signs of illness similar to those of human influenza virus infection. To quantify lethargy, we previously established video monitoring as a more sensitive method than the commonly used manual scoring methodology for ferrets infected with influenza virus. Video monitoring is simple to set-up, but its adoption by other laboratories is restricted by the need to purchase costly commercial software, EthoVision® XT, to analyse activity. To broaden the use of video monitoring method in ferrets, we assessed Swarm Sight, a free open-access programme, for analysing activity changes in ferrets infected with seasonal influenza A(H1N1), A(H1N1) pdm09, A(H3N2) and B virus. Swarm Sight could differentiate between the various levels of lethargy associated with the infection of different influenza viru.. Read More»
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Jan 01, 1970
Accepted Date: Jan 01, 1970
Published Date: Jan 01, 1970