Tanzania
Research Article
Pupillary Light Reflex as an Objective Biomarker for Early Identification of Blast-Induced mTBI
Author(s): José E Capó- Aponte, Thomas G Urosevich, David V Walsh, Leonard A Temme and Aaron K TarbettJosé E Capó- Aponte, Thomas G Urosevich, David V Walsh, Leonard A Temme and Aaron K Tarbett
Purpose: There is an increase in mild traumatic brain injury (mTBI) in US Warfighters resulting from exposure to explosive devices. However, there is a lack of objective biomarkers to accurately identify mTBI in order to make a return-to-duty (RTD) determination in the battlefield. The present study examined pupillary light reflex (PLR) as a potential objective biomarker for early identification of mTBI.
Methods: The PLR-200™ monocular infrared pupillometer was used to quantify PLR under mesopic conditions in 20 U.S. military personnel with blast induced-mTBI and 20 age-matched non-TBI military personnel. Eight PLR parameters were assessed: maximum diameter; minimum diameter; percent of constriction; constriction latency; average constriction velocity; maximum constriction velocity; 75% recovery time; average dilation velocity.
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DOI:
10.4172/2165-7939.S4-004
Journal of Spine received 2022 citations as per Google Scholar report