Australia						                            
                            
						
 Review Article
												An Open Label Study investigating the Efficacy of  Hypericum perforatum  Special Extract (ZE117), Nicotine Patches and Combination (ZE117)/ Nicotine Patches for Smoking Cessation 						
Author(s): Con Stough, Andrew Scholey, Christina Kure, Joanne Tarasuik, Marni Kras, Andrea Zangara and David CamfieldCon Stough, Andrew Scholey, Christina Kure, Joanne Tarasuik, Marni Kras, Andrea Zangara and David Camfield             
						
												
				 Introduction: Nicotine addiction has become one of the largest international health problems, increasing the risk of cardiovascular disease, cancers, and respiratory diseases. There are several treatments available for smoking cessation with the most common transdermal nicotine Replacement and anti-depressants. However current treatments are only mildly efficacious and have side effects which lead to a decrease in their effectiveness. Additional treatments for smoking cessation with lower side effects are required. Methods: We examined the efficacy of Remotiv® (Hypericum perforatum Special Extract - ZE117) compared to Nicabate® CQ Nicotine Replacement Therapy (NRT) and combination ZE117/NRT for smoking cessation over a treatment time of 10 weeks. Given the different pharmacological profiles of Ze117 and NRT it was expected that a combination treatment would be most efficacious.. Read More»
				  
												DOI:
												 10.4172/2327-5162.1000147 
																	  
Alternative & Integrative Medicine received 476 citations as per Google Scholar report