Portugal						                            
                            
						
 Case Report
												Tiapride Associated Toxic Epidermal Necrolysis in an HIV-Infected Patient 						
Author(s): Paulo  Andrade, Nuno Rocha  Pereira, Cândida  Abreu, Paula  Egipto, Daniel  Moura and António  SarmentoPaulo  Andrade, Nuno Rocha  Pereira, Cândida  Abreu, Paula  Egipto, Daniel  Moura and António  Sarmento             
						
												
				 Toxic epidermal necrolysis is a rare but severe and often fatal adverse cutaneous drug reaction. Early diagnosis and prompt discontinuation of the culprit drug is of the utmost importance, making drug causality assessment the mainstay when managing this condition. We present the first reported case of toxic epidermal necrolysis induced by tiapride, in a 43 year-old male Caucasian with a history of liver cirrhosis and HIV infection. This case report should raise awareness on the medical community to a potentially fatal reaction to a frequently prescribed drug in alcoholic patients. It also underlines the importance of further research regarding HIV infection, immune deregulation and adverse cutaneous drug reactions.
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												DOI:
												 10.4172/2165-7920.1000323 
																	  
Journal of Clinical Case Reports received 1345 citations as per Google Scholar report