Journal of Hypertension: Open Access

Chih-Cherng Lu

Publications

• Research Article
  Water Ingestion Increases Plasma Somatostatin in the Course of the Osmopressor Response
  Author(s): You Hsiang Chu, Yu-Juei Hsu, Chih-Cherng Lu, Herng Sheng Lee, Tso-Chou Lin, Shung-Tai Ho, Che-Se Tung and Ching-Jiunn TsengYou Hsiang Chu, Yu-Juei Hsu, Chih-Cherng Lu, Herng Sheng Lee, Tso-Chou Lin, Shung-Tai Ho, Che-Se Tung and Ching-Jiunn Tseng
  
  Background: Studies in patients with an impaired efferent baroreflex led to the discovery that ingestion of water induces a robust increase in blood pressure and vascular resistance. This response was also present in healthy subjects with intact baroreflexes. We aimed to clarify the physiological role of the osmopressor response by determining the change of plasma somatostatin after water ingestion in young healthy subjects. Methods and results: In a randomized, controlled, crossover fashion, 17 young healthy subjects (aged 22-35 years) ingested either 500 or 50 mL of water. Heart rate, blood pressure, cardiac index, and total peripheral vascular resistance were measured using a Finometer hemodynamic monitor. Blood sampling was performed at 5 min before and at 25 and 50 min after water ingestion. Plasma somatostatin was measured by ELISA. At 2.. Read More»
  DOI: 10.4172/2167-1095.1000114

  Abstract PDF