Molecular Biomarkers & Diagnosis

ISSN: 2155-9929

Open Access

Chalupova L

Department of Animal Physiology and Immunology, Faculty of Science,
Kamenice 753/5, 625 00 Brno
Czech Republic

  • Research Article
    CTRP1: A Molecular Link between Obesity and Hypertension
    Author(s): Chalupova L, Halupova L, Zakovska A, Krejci G and Stejskal DChalupova L, Halupova L, Zakovska A, Krejci G and Stejskal D

    Background: CTRP1, a recently identified adipokine, was found to stimulate aldosterone production. Serum CTRP1 and plasma Aldosterone levels were significantly increased in patients with diabetes mellitus and metabolic syndrome. Therefore, it would be interesting to investigate whether the secretion of CTRP1 in human serum is associated with hypertension as well as with diabetes mellitus. Aim: This study evaluated serum CTRP1 and aldosterone concentrations in healthy individuals and in patients with diabetic nephropathy. Methods: Serum samples from 32 healthy individuals and 44 patients with diabetic nephropathy were measured for CTRP1, Aldosterone, diabetes-related biomarkers and renal disease-related biomarkers by enzyme-linked immunosorbent assay (ELISA). Results: Correlation analyses showed.. Read More»
    DOI: 10.4172/2155-9929.1000289

    Abstract PDF

Relevant Topics

Google Scholar citation report
Citations: 2054

Molecular Biomarkers & Diagnosis received 2054 citations as per Google Scholar report

Molecular Biomarkers & Diagnosis peer review process verified at publons

Indexed In

arrow_upward arrow_upward