Journal of Molecular Biomarkers & Diagnosis

Bruno R

Publications

• Research Article
  Osteochondrosis-Related Gene Expression in Equine Leukocytes Differs among Affected Joints in Foals
  Author(s): Serteyn D, Piquemal D, Mendoza L, Caudron I, Noguier F, Bruno R, Sandersen C and Lejeune JPSerteyn D, Piquemal D, Mendoza L, Caudron I, Noguier F, Bruno R, Sandersen C and Lejeune JP
  
  Osteochondrosis (OC) is a developmental disease in horses with a significant impact on the horse’s welfare and performance. Previously, differentially expressed genes in leukocytes of OC-affected have been identified and were differentially expressed in horses of different ages when compared to their age-matched controls.As the time course of the development of OC lesions seems to be joint dependent,the aim of this study is to compare in young OCaffected horses (between 8 to 12 months), the different expression of selected genes depending the joints involved.The expression of OC-related genes were analysed by rt-PCR and subsequent statistical analysis (ΔΔCT) in the leukocytes of 30 Belgian Warmblood horses aged between 8 to 12 months divided in groups depending the affected joints (fetlock, hock and stifle).In the three groups, expression of ApoB-3G, MGAT4A, B4GALT6 .. Read More»
  DOI: 10.4172/2155-9929.1000189

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