Alternative & Integrative Medicine

Agnieszka Sobczak

Publications

• Mini Review
  Basic Studies on Chemopreventive Properties of Quercetin and Curcumin and Other Plant-origin Compounds in Ovarian Cancer Cells-A Mini-review
  Author(s): Radosław Kujawski, Justyna Baraniak, Marcin Ożarowski, Małgorzata Kujawska, Magdalena Borowska, Malgorzata Kania, Joanna Bartkowiak- Wieczorek, Agnieszka Sobczak, Agnieszka Gryszczyńska, Katarzyna Manikowska, Joanna Liberska, Joanna Cichocka, Michał Szulc and Piotr RuszkowskiRadosław Kujawski, Justyna Baraniak, Marcin Ożarowski, Małgorzata Kujawska, Magdalena Borowska, Malgorzata Kania, Joanna Bartkowiak- Wieczorek, Agnieszka Sobczak, Agnieszka Gryszczyńska, Katarzyna Manikowska, Joanna Liberska, Joanna Cichocka, Michał Szulc and Piotr Ruszkowski
  
  Despite the increasing number of studies on the molecular actions of quercetin and curcumin, their anticancer efficacy, safety and molecular aspects of chemopreventive action in the ovarian cancer prophylaxis or treatment and also their potential in the sensitization to cytostatics used in the clinical practice remains still not clearly understood. Based on basic studies we have summarized evidences for inhibitory activities of several often studied plantorigin bio-active compounds (mostly quercetin and curcumin) against ovarian cancer cells proliferation, their mechanisms of action as well as their strong potential to sensitization of ovarian cancer cells to the presence of several platinum-based cytostatics - cisplatin and oxaliplatin. Up to date only several dietary, clinical (cohort and case–control) studies evaluating the association of some flavonoids (mostly non.. Read More»
  DOI: 10.4172/2327-5162.1000238

  Abstract PDF