GET THE APP

..

Medicinal Chemistry

ISSN: 2161-0444

Open Access

Volume 10, Issue 10 (2020)

Research Pages: 1 - 4

Determination of Optimum Spacing and Harvesting Age of Citron Scented Gum (Eucalyptus citriodora H.) for Maximum Biomass and Essential Oil Yield at Wondo Genet, South Ethiopia

Desta Fikadu Egata* and Wondimkun Dikir Desta

The experiment was conducted at Wondo Genet south Ethiopia for three years. The study was aimed for determination of optimum plant spacing
and harvesting age on E. citriodora. The treatment consists of three levels of harvesting ages and four levels of plant spacing. The character that
manifested for data collection is: plant height, leaf weight/plant stem weight/plant leaf to stem ratio, leaf and stem yield/ha, essential oil content
and essential oil yield/ha were collected. The whole plant had been cut using sharp saw at 20 cm height above the ground and essential oil was
extracted from the leaf part. The results of the study revealed that harvesting age had very highly significant effect on plant height, fresh leaf to
stem ratio, essential oil content and essential oil yield/hectare. Spacing had a very high significant effect on fresh leaf yield/hectare and fresh
stem/hectare. The interaction effect of spacing and harvesting age had significant effect on essential oil content. The highest leaf weight/pant was
obtained with spacing of 1.5 m and 2 m between plants and raw respectively. Maximum fresh leaf yield/hectare was obtained with narrower spacing
(1.5 m between plant and row) and the highest essential oil yield/hectare was obtained when the plant harvested at 10 months after transplanting
but it was not significantly different with harvesting age at 9 months after transplanting. Based on the overall result use of plant spacing 1.5 × 2 m
and 9 to 10 MATS were recommended for citron scented for Wondo Genet and its vicinity.

Research Pages: 1 - 5

Ethiopian Rue (Ruta chalapensis L.) Genotypes Morphological and Biological Performance at Different Locations of Southern Ethiopia

Desta Fikadu Egata* and Aynalem Gebre Gosa

Rue is an aromatic is evergreen plant used for multipurpose that used for traditional medicine and in Ethiopia mainly used flavoring coffee addition to its medicinal
benefit. There is limitation of knowledge, experience, modern scientific evidences and information on Ethiopian R. chalenpesnsis genotypes because the
experiment was undergone the aim to minimize the aforementioned gaps. The experiment was held for one year in 2019 up to 2020 G.C. at three different locations
using 10 (ten) selected promising superior genotypes from selected during characterization of accessions. Selected genotypes were tested using Randomized
Complete Block Design following the procedures of Gomez and Gomez in three replications. Rue genotypes were planted in six rows of 3-meter length on the
commencement of main rainy season using 60 cm between plant and row spacing. Data was collected from different traits such as; plant height, number of
branches/plants, fresh leaf weight/branch, fresh leaf weight/plant, leaf to stem ratio, leaf yield/ha, percent essential oil content and essential oil yield/ha. All tested
traits very significantly affected by locations and genotypes during this experiment. The phenology of the genotypes is highly affected by location different; rue
genotypes give more fruits early at high land and more leaves at low lands. Maximum leaf yield and leaf essential oil yield/ha was obtained at Arba Minch and
maximum fruit essential oil yield/ha at Wondo genet from genotypes 1and 5 respectively. Based on this experiment result high altitude agroecology is more suitable
for production and low altitude is for leaf production.

Research Pages: 1 - 5

Synthesis and Anticonvulsant Activity of Oxadiazole Derivatives Incorporating Phthalazin-1,4 (2H, 3H)-dione Scaffolds

Ehab M. Mostafa, Yomna A. Salem, Ahmed M. Mansour, and Rezk R. Ayyad5*

In this present work, we prepared the 2- (2-mercapto oxadiazole phthalazin (2H, 3H) -1,4-dione (1) and its salt (2) from 2-hydrazino
carbonylmethylphthalazine (2H, 3H) -dione which resulted from condensation of carbondisulfide and potassium hydroxide in ethanol. Also we
prepared 2- (2-mercapto oxadiazole-6,7 –dichloro phthalazin (2H, 3H) -1,4-dione (3) and its salt (4). The two salts (2) and (4) reacted with different
alkylchloroacetates to produce compounds (5 a-f) and (6 a-f) these compounds tested as anticonvulsant drugs, its revealed anticonvulsant activity
compared with phenobarbitone as refrence drug.

Commentary Pages: 1 - 1

Strategy to Recoup Lost Single-Cell RNA-Sequencing Data

Sowmya Uttam*

Sequencing RNA from singular cells can uncover a lot of data about what those cells are doing in the body. MIT analysts have now enormously supported the measure of data gathered from every one of those cells, by altering the usually utilized Seq-Well method. With their new methodology, the MIT group could remove 10 fold the amount of data from every cell in an example. This expansion should empower researchers to learn significantly more about the qualities that are communicated in every cell, and help them to find unobtrusive however basic contrasts among sound and broken cells.

Editorial Pages: 1 - 1

Better Impetuses for a Supportable Bioeconomy

Sowmya Uttam*

Analysts need to make alleged zeolites more proficient. Today, these mixes are as of now fundamental added substances in the synthetic business and have been utilized as impetuses in petroleum processing plants since the 1960s. Presently the analysts advocate giving more consideration to the exemplary zeolites. These, they declare, would even can possibly make a bioeconomy dependent on sustainable assets conceivable. To change our petroleum derivative based economy into a reasonable bioeconomy, we should supplant fossil assets with sustainable crude materials. However, oil, the beginning material for various results of the substance business, can't just be traded for wood, maize, and straw, since plants comprise of totally various types of particles than "dark gold." To control cars and empower the creation of an expansive scope of plastics or medications, inexhaustible crude materials should initially go through a synthetic change. Here assistance is given by impetuses, that is, substances that drive compound responses or make them conceivable in any case.

Google Scholar citation report
Citations: 6627

Medicinal Chemistry received 6627 citations as per Google Scholar report

Medicinal Chemistry peer review process verified at publons

Indexed In

 
arrow_upward arrow_upward