About 20%-30% of patients with acute pancreatitis have a severe disease and mortality rate among inpatients were 15%. There are many causes of Acute Pancreatitis (AP), but most common cause of AP is an alcohol. In Mongolia, relatively young men suffer from alcohol-induced pancreatitis. Factors contributing to the development of necrosis in acute pancreatitis include alcohol abuse, prolonged alcohol use, delayed hospitalization, and delayed treatment. In our study, following clinical signs and laboratory findings are effective in distinguishing severe forms of acute necrotizing pancreatitis, early diagnosis, and assessment of prognosis. Laboratory tests parameters include of new recording system: increase in white blood cells, procalcitonin, serum amylase, serum LDH, serum lipase, C-reactive protein and a decrease in hematocrit, serum calcium.