The study was aiming to investigate the effect of partial replacement of cement by cattle bone ash (CBA) in a concrete property. Complete silicate analysis of CBA shows that the material has high calcium oxide content (43.26%) which is the major oxide compound of cement. A C-25 concrete grade was selected for this study. The Normal consistency, setting time, soundness of cement paste, slump, compressive strength and density of concrete tests are done with (0%), 5%, 10%, 15% and 20% cement replacement with cattle bone ash. The compressive strength of concrete was done by curing 15 cm × 15 cm × 15 cm cube concrete specimens underwater for 3,7,28 and 56 days. The normal consistency of the cement paste increases as the percentage of the cattle bone ash increases in the paste attributed to high water absorption of CBA than OPC. The initial and final setting time of cement paste increase as the percentage of replacement of cement with bone ash. The slump of concrete decreases at 0% to 10% CBA mix and increases in 15% to 20% CBA mix. From the results, the partial replacement of Ordinary Portland Cement with Bone ash shows a gradual decrease in the compressive strength of concrete. The concrete density decreases as the percentage of bone ash increases. The use of cattle bone waste as an additive or supplementary cementing material production has vital importance to produce low-cost concrete and helps to conserve materials needed for cement production.