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Journal of AIDS & Clinical Research

ISSN: 2155-6113

Open Access

Current Issue

Volume 12, Issue 2 (2021)

    Editor Note Pages: 1 - 1

    HIV/AIDS: Key facts

    Eleni Stewart*

    HIV stands for human immunodeficiency virus, which is the virus that causes HIV infection. The abbreviation “HIV” can refer to the virus or to HIV infection.  AIDS stands for acquired immunodeficiency syndrome. AIDS is the most advanced stage of HIV infection. HIV attacks and destroys the infection-fighting CD4 cells of the immune system. The loss of CD4 cells makes it difficult for the body to fight off infections and certain cancers Without treatment, HIV can gradually destroy the immune system and advance to AIDS. This article deals with the Key facts related to the Disease

    Editorial Pages: 1 - 1

    Editorial Note for the Journal of AIDS & Clinical Research

    Cynthia C

    Without continual growth and progress, such words as improvement, achievement, and success have no meaning. Founded in 2010, Journal of AIDS & Clinical Research (ISSN: 2155-6113) is growing continuously. It is our pleasure to announce that in the beginning of year 2020, First edition i.e. volume 12 Issue 1 was published online on time and the print issues were also brought out and dispatched within 30 days of publishing the issue online. 

    Editorial Pages: 1 - 1

    Diagnosis HIV

    Micheal Pernatte*

    Antiretroviral medicines are used to treat HIV. They work by stopping the virus replicating in the body, allowing the immune system to repair itself and preventing  further damage. No cure exists for AIDS, but strict adherence to antiretroviral regimens (ARVs) can dramatically slow the disease's progress as well as  prevent secondary infections and complications. 

    Research Pages: 1 - 5

    Determinants of HIV/AIDS Disclosure in Pediatrics Age from 5-14 Years on ART

    Wolde Melese Ayele

    Background: One of the most difficult issues that families with HIV-infected children and their medical providers face is disclosing their HIV status to their child. Despite emerging evidence of the benefits of disclosure, its prevalence is low, and the predictors for non-disclosure remain clinical dilemma. Therefore, this study aimed to explore determinants of HIV status disclosure among 5-14 years age children in Dessie town, Ethiopia. Methods: Health facility based unmatched case-control study was conducted from January 1 to February 30, 2019. Interviewer based questionnaire was used for data collection from a total of 387 children on ART /care givers pairs. Bivariable and multivariable logistic regression analysis were carried out using SPSS version 23 software. Result: A total of 374 children/caregiver pairs were included in the study, making 96.6% 96.6% of response rate. In multivariable logistic regression model, presence of organizational support (AOR=27.77, 95% CI: 12.472, 61.819), child age of 10 to 14 years (AOR= 3, 95% CI; 1.423, 6.536) and conducting of discussion with health care providers (AOR=17.65, 95% CI; 6.611, 47.002) predicted children’s HIV disclosure status. Conclusion: Presence of organizational support, child age of 10 to 14 years, and care givers discussion with health care providers were statistically significantly associated with HIV status disclosure. Further qualitative and community based research may reveal more on these and other factors; organizational support strategy may address some of these determinants.

    Editorial Pages: 1 - 11

    HIV Stigma

    Prabhas Maurya*

    There is a cyclical relationship between stigma and HIV; people who experience stigma and discrimination are marginalised and

    made more vulnerable to HIV, while those living with HIV are more vulnerable to experiencing stigma and discrimination.

    Myths and misinformation increase the stigma and discrimination surrounding HIV and AIDS.

    Roughly one in eight people living with HIV is being denied health services because of stigma and discrimination.

    Adopting a human rights approach to HIV and AIDS is in the best interests of public health and is key to eradicating stigma and discrimination

    Volume 12, Issue 3 (2021)

      Editorial Pages: 1 - 1

      J AIDS Clin Res Editorial Note

      Steve Lance

      Without continual growth and progress, such words as improvement, achievement, and success have no meaning. Founded in 2010, Journal of AIDS & Clinical Research (ISSN: 2155-6113) is growing continuously. It is our pleasure to announce that in the beginning of year 2020, First edition i.e. volume 12 Issue 1 was published online on time and the print issues were also brought out and dispatched within 30 days of publishing the issue online. 

      Editorial Pages: 1 - 1

      HIV Stigma in the World

      Prabhas Maurya

      There is a cyclical relationship between stigma and HIV; people who experience stigma and discrimination are marginalised and  made more vulnerable to HIV, while those living with HIV are more vulnerable to experiencing stigma and discrimination. Myths and misinformation increase the stigma and discrimination surrounding HIV and AIDS. Roughly one in eight people living with HIV is being denied health services because of stigma and discrimination. Adopting a human rights approach to HIV and AIDS is in the best interests of public health and is key to eradicating stigma and discrimination

      Editorial Pages: 1 - 1

      HIV/AIDS: Key facts and Data

      Eleni Stewart

      HIV stands for human immunodeficiency virus, which is the virus that causes HIV infection. The abbreviation “HIV” can refer to the virus or to HIV infection. AIDS stands for acquired immunodeficiency syndrome. AIDS is the most advanced stage of HIV infection. HIV attacks and destroys the infection-fighting CD4 cells of the immune system. The loss of CD4 cells makes it difficult for the body to fight off infections and certain cancer Without treatment, HIV can gradually destroy the immune system and advance to AIDS. This article deals with the Key facts related to the Disease

      Editorial Pages: 1 - 9

      Editorial

      Cynthia C

      There is a cyclical relationship between stigma and HIV; people who experience stigma and discrimination are marginalised and made more vulnerable to HIV, while those living with HIV are more vulnerable to experiencing stigma and discrimination. Myths and misinformation increase the stigma and discrimination surrounding HIV and AIDS. Roughly one in eight people living with HIV is being denied health services because of stigma and discrimination. Adopting a human rights approach to HIV and AIDS is in the best interests of public health and is key to eradicating stigma and discrimination

      Research Article Pages: 1 - 6

      Statistical Modeling of Survival of Tuberculosis Infected HIV Patients Treated with Antiretroviral Treatment: A Caseof Felege Hiwot Referral Hospital, Bahir Dar, Ethiopia

      Senait Cherie Adegeh* and Essey Kebede

      Objectives: This study focused on modeling of the survival of tuberculosis infected HIV patients treated with antiretroviral treatment in Felege Hiwot referral hospital. Methods: Human Immunodeficiency Virus/tuberculosis (HIV/TB) co-infected patients aged 15 years and above were selected using simple random sampling and included in the study. The sample size for this study was 314 patients. Kaplan-Meier survival curves and Log-Rank test were used to compare the survival experience of different category of patients, and proportional hazards Cox proportional hazards model was employed to identify independent predictors of survival of HIV/TB patients. Results: Of the total samples 66 (21.0%) were died and 248 (79.0%) were censored. The results of single covariate analysis show that the variables: sex, age, marital status, literacy status, employment status, family size number of living rooms, CD4 count, baseline body weight, WHO stage, regimen type, knowledge about ART, condom use, drug use, alcohol intake, tuberclosis category and regimen change were found to be factors that significantly influence the survival of HIV/TB co-infected patients at 25% significance level. From the Cox regression analysis, the independent factors CD4 count, tuberculosis category, number of living rooms, employment status, alcohol and tobacco use were significant. The odds of being at risk of death for patients who does not smoke tobacco is 47.5% less than those who use tobacco. Conclusions: In conclusion, baseline CD4 count, tuberculosis category, number of living rooms, employment status, alcohol and tobacco use were the main factors significantly influencing the survival time of HIV/TB co-infected patients. We recommend that, there should be a careful monitoring of patients with low CD4 count, less than two numbers of rooms, disseminated and extra-pulmonary TB, having risk behaviors like drinking alcohol and not being employed is necessary to improve survival of HIV/TB co-infected patients.

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