Journal of Genetics and DNA Research

Solute binding proteins and their cognate ligands: structure, function and their role in functional annotation

Abstract

Umesh Yadava

The uptake of exogenous solutes is mediated by transport systems embedded in the plasma membrane and drive active transport even at μM to nM solute concentrations. In many of these systems a periplasmic Solute-Binding Protein (SBP) is utilized to bind their cognate ligands with high affinity and deliver them to the membrane bound translocator subunits.