K. Manikandakumar, K. Gokul Raj, S. Muthukumaran and R. Srikumar
We describe a novel way of applying Chaos Game Representation (CGR) method to protein sequences of different families by considering the amino acids into three secondary structure groups of residues. The present study to identify the patterns of the secondary structure of family of protein sequences for different ratios and to analyze to apply CGR method to protein structures, so as to find out any intrinsic self-similar pattern exhibited in the CGR plot. Further, we find that the sequences of different protein families belonging to all the four major structural classes namely, all α, all β, α plus β and α by β produce a similar kind of self-similar fractal structure. In a broader sense, is there any way to obtain a single graphical representation depicting any intrinsic self-similar pattern exhibited by the different protein families?
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Journal of Computer Science & Systems Biology received 2279 citations as per Google Scholar report
