Journal of Nephrology & Therapeutics

Renal Injury in Calcium-Alkali Syndrome

Abstract

Yoshiyuki Morishita, Hiromichi Yoshizawa and Eiji Kusano

Calcium-alkali syndrome is characterized by hypercalcemia, renal injury and metabolic alkalosis. Calcium-alkali syndrome caused by calcium carbonate and vitamin D has been increasing in association with their growing use for the treatment and prevention of osteoporosis. Renal injury is the most critical factor determining the severity and prognosis of this syndrome. This review focuses on the mechanism and clinical aspects of renal injury in calcium-alkali syndrome.