Journal of Genetics and Genomes

Packaging of the Genome into the Cell Nucleus

Abstract

Saban Tekin*

Chromatin immunoprecipitation (ChIP) tests examine histone mutations and genomic DNA sequences bound to specific regulatory proteins. In ChIP, protein-DNA complexes are linked to in vivo, are immune, purified, and amplified for genetic targeting and developer of known targets or to identify new target sequences. In a microarray-based, ChIP-on-Chip, DNA immunoprecipitated DNA is labeled and packaged in high-resolution microarrays.