Journal of Nephrology & Therapeutics

ISSN: 2161-0959

Open Access

Omeprazole Induced Acute Interstitial Nephritis in an Adolescent


Damien Noone *,Chia Wei Teoh ,Anthony M Dorman ,Atif Awan

Proton pump inhibitors (PPIs) have emerged as a common cause of drug induced acute interstitial nephritis (AIN) in adults. We present a 15-year-old girl with severe acute kidney injury and biopsy proven AIN attributable to omeprazole. Withdrawal of the drug and steroid therapy affected a recovery of renal function. As the use of PPIs increases in paediatrics, it is important to be aware of this rare but serious side effect.


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