Background: The availability of medication related to HIV treatment in the world is one of the substantial improvements for reaching USAID’s 90-90 targets. Among the 90% of patients who have awareness about their disease, 90% of them are accessing their treatment and patients who got appropriate treatment have a suppressed viral load and improved CD4 cell count. Therefore, the main objective of the current study was to investigate the drug resistance and quality of life and associated factors for people living with HIV at first-line regimens at public hospitals in the Amhara region, Ethiopia.
Methods: A retrospective cohort study design was conducted on 700 adult HIV-infected patients under treatment at first-line regimes, who were followed up in 17 public hospitals in the Amhara region. A multivariate linear regression analysis was used for current study.
Results: Of the 700 patients included in the current analyses, 59.5% (n=358) reported no impairment in self-care, while 63.1% (n=380) were extremely anxious/depressed. The overall expected EQ-5D utility score and Visual Analog Scale (EQ-VAS) scores were 0.388 0.41 and 66.20 17.22 respectively. The current study indicated that the covariates sex, age of patients, level of education, visiting times, disclosure status of the disease, and substance use significantly affected the quality of life of people living with HIV and under treatment at first-line regimens. Hence, the higher the CD4 cell count and the less detectable viral load lead to the good quality of life of people living with HIV.
Conclusions: This study indicates that certain covariates have been identified as statistically significant predictors for the variable of study (quality of life) of HIV-positive people. The findings obtained in the current investigation help policymakers to revise the current
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