Journal of Molecular Histology & Medical Physiology

Open Access

A Case of Evan’s Syndrome Presented as Megaloblastic Anaemia and Hypothyroidism


Jabir PK and Madhusudhan U

Even though Evan ’ s syndrome is idiopathic it can be associated with many other diseases including Polyglandular Autoimmune Syndromes (PGAS) and Hashimoto’s thyroiditis. It is a rare syndrome manifested as autoimmune hemolytic anemia and thrombocytopenia. Since the underlying cause is autoimmune it can be presented as severe hemolytic anemia and many clusters of diseases which share a common pathogenesis. Here we present a case of a 32-year-old female patient with severe hemolytic anemia and found to be Evans syndrome with polyglandular involvement.


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