Anupa Mary Job
St. John├ó┬?┬?s Medical College, India
Posters & Accepted Abstracts: J Cancer Sci Ther
Introduction: Gynaecological malignancies account for 25% of all new cancers diagnosed among women up to 65 years in India, the most common being carcinomas of cervix, breast and ovary. Cutaneous metastasis are commonly noted in breast malignancies (23.9%) but are rarely reported in genital malignancies (0.88%). Ambiguity still prevails over their pathomechanism. We report six unusual presentations of cutaneous metastasis in a setting of primary gynaecological malignancy. Cases: Case1 is a 45 years old, with carcinoma ovary with multiple papulonodular lesions in a zosteriform pattern below umbilicus; Case 2 is a 52 year old with vulvar carcinoma with multiple papulonodules around surgical incision site; Case 3 include a 31 year old with solitary ulcerated nodule overlying the transverse surgical incision site over the abdomen; Case 4 is a 63 year old with cervical carcinoma with vulvar ulcerated plaques; Case 5 is a 64 year old with carcinoma breast with solitary erythematous papule on the right infraclavicular area and; Case 6 is a 47 year old with carcinoma breast with multiple popular lesions in a zosteriform pattern around the site of incision for mastectomy. Conclusion: a) Cutaneous metastasis is an essential marker for prognosis in gynecologic malignancy. Earlier the time interval between diagnosis of gynecological malignancy and occurrence of skin metastasis worse will be the prognosis. b) Emphasis on regular breast and genital examination in clinical practice is needed. Consider a diagnosis of cutaneous metastasis while evaluating papulonodular lesions occurring in a setting of an occult malignancy. c) Therapeutic port access sites metastasis are often missed as these are usually deep seated lesions which are better palpable than seen. This case series shows various manifestations of cutaneous metastasis in gynaecologic malignancies.
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