Trends in antibiotics resistance of Staphylococcus aureus at a teaching hospital, China, 2011-2016

Joint Event on 14^th International Conference on Microbial Interactions & Microbial Ecology & 11^th Edition of International Conference on Advances in Microbiology and Public Health

August 19-20, 2019 Vienna, Austria

Tingting Mao

Zhengzhou University, China

Posters & Accepted Abstracts: J Med Microb Diagn

Abstract :

Objective: The purpose of this study was to describe the antibiotics resistance trends of Staphylococcus aureus (S. aureus) gathered from a general hospital in Zhengzhou city, Henan province, China during 2011-2016.

Methods: The resistance of 1406 S. aureus strains detected by Zhuhai Deere DL-96 Bacteria Identification System from 19,260 specimens were analyzed by Minimum inhibitory concentration (MICs). Statistical analyses were performed using the chi-squared test and the chi-squared test for trend.

Results: During the study period (2011-2016), the overall detection rate of S. aureus was 7.3% (1406/19,260), of which rates of infected S. aureus increased from 6.72% in 2011 to 8.62% in 2016 (p=0.0421), and resistance rates of mostly (14/18) detected antibiotics to S. aureus showed a significant downward trend (all-p<0.05). Among these antibiotics resistance to cefoxitin decreased from 69.79% in 2011 to 41.9% in 2016. The isolated methicillin-resistant S. aureus (MRSA) overall detection rate was 43.1% (606/1406), which showed a downward trend of resistance rates to 13 antibiotics (all-p<0.05), of which levofloxacin fastest decreased from 76.47% in 2011 to 50.89% in 2016. No isolate was detected to be resistant to linezolid and vancomycin.

Conclusion: The epidemiological characteristics of S. aureus, particularly MRSA, are changing rapidly. Although the resistance rates were decreasing, the infection caused by S. aureus still remains a widely spread condition. Continuous surveillance and abiding to the rules of using antibiotics are necessary.

Biography :

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