Gamal Abdul Hamid, Safa Shukry and Iman Bin Hiraz
National Oncology Center, Yemen
Posters & Accepted Abstracts: J Cancer Sci Ther
Objective: To evaluate the frequency of involvement of bone marrow with hematological disorders and to observe the significance of bone marrow examination in diagnosis and prognosis of patients admitted and attended Aden Hematology-Oncology Center with limited resources. Bone marrow aspiration was the most effective method for studying morphological details and was able to diagnose most of the cases except cases with myelofibrosis and severe pancytopenia which yielded dry tap for which trephine biopsy was diagnostic. Method: This was a retrospective study from January 2013 to December 2014. Results: A total of 260 pathological BME were recorded from patients aged 1 year to 80 years with a mean age of 34.8 years and M:F ratio of 1.4:1 The main findings were acute lymphoblastic leukemia (ALL) 25%, acute myeloblastic leukemia (AML) 21.5%, chronic myeloid leukemia (CML) 20%, malignant lymphoma in 10% and myelodysplastic syndrome (MDS) in 9.6%. Conclusion: Both bone marrow aspiration and biopsy was found to be complementary to each other and play an important role in diagnosis of hematological malignancies in centers with limited resources.
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