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Role of contrast enhanced spectral digital mammography in follow up of breast cancer patients after the conservative surgery and its impact on management
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Cancer Science & Therapy

ISSN: 1948-5956

Open Access

Role of contrast enhanced spectral digital mammography in follow up of breast cancer patients after the conservative surgery and its impact on management


3rd World Congress on Women’s Health & Breast Cancer

October 03-05, 2016 London, UK

Asmaa Mahmoud Abdel Magied, Lamiaa Adel Salah Eldin and Emad Salah Eldin Khalaf

Cairo University, Egypt

Posters & Accepted Abstracts: J Cancer Sci Ther

Abstract :

Objective: To evaluate the diagnostic accuracy of adding contrast enhanced spectral digital mammography to the conventional sonomammography in detection of recurrent breast cancer after conservation surgery Patients & Methods: This study included 40 female patients presenting with indeterminate/suspicious breast lump after breast conservative surgery. Their age varied from 34 to 60 years (mean age: 50.3 years). All of the cases (40/40 cases) were subjected to digital mammography and B-mode ultrasonography followed by dual energy contrast enhanced spectral mammography (CESM) within 2 weeks. Results of histo-pathological examinations of surgical or biopsy specimens were obtained and served as the gold standard. Results: The surgical and pathological results of our patients revealed 12/40 (30.0%) benign lesions and 28/40 (70.0%) malignant lesions. The sonomammography results were 18/40 (45.0%) benign lesions (BIRADS 3) and 22/40 (55.0%) malignant lesions (BIRADS 4 and 5). 20 lesions were true positives, 2 lesions were false positive, 8 lesions were false negatives and 10 lesions were true negatives with sensitivity of 71.4% with specificity of 71.4%. The CESM results were 14/40 (35%) benign lesions (BIRADS 3) and 26/40 (65%) malignant lesions (BIRADS 4 and 5). 24 lesions were true positives, 2 lesions were false positive, 10 were true negatives and 4 lesions were false negatives with sensitivity of 85.7% and specificity of 71.4 %. Conclusion: CESM is a promising tool for increasing the sensitivity and the diagnostic accuracy of ultrasound and mammography in follow up of patients with breast conservative surgery.

Biography :

Email: asmaa_dr79@hotmail.com

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