Regular aspirin use and stomach cancer risk in China

3^rd International Conference on Genomics & Pharmacogenomics

September 21-23, 2015 San Antonio, USA

Yue Wang

Liaoning Cancer Hospital and Institute, China

Posters-Accepted Abstracts: J Mol Genet Med

Abstract :

Epidemiological studies on aspirin and stomach cancer have been inconclusive. The purpose of our study was to investigate the association between aspirin and stomach cancer in China. A 1:2 matched case-control study was conducted in four large medical centers. A self-designed questionnaire was used to collect information. Unconditional logistic regression was used to compute crude and adjusted Odds Ratios (ORs) with 95% Confidence Intervals (CIs). Our study indicated that risk of stomach cancer was greatly reduced for regular aspirin user (OR=0.62; 95% CI 0.42-0.80). Specifically, dosage and tablet-years of use were associated with lower risk (OR=0.54; 95% CI 0.29�0.84 for �7 tabs/week; OR=0.47; 95% CI 0.32-0.81 for �10 tablet years, respectively). Furthermore, the finding was strengthened by stratified studies of gender, smoking status, Body Mass Index (BMI) and Helicobacter pylori. Our study confirmed that regular aspirin use is a protective factor to stomach cancer.

Biography :

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